Alignment Analysis
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 Tools    >> BEPIBLAST: B cell EPItope prediction using a BLAST-based module

Paste Sequence in Fasta format (Replace Example)
Or upload fasta file:

Search Epitopes
Epitope Feature
Peptide length:
Output options

Only neutralizing

Map in sequence

Min. Identity ≥

  • Ras-Carmona A, Lehmann AA, Lehmann PV & Reche PA (2022). Prediction of B cell epitopes in proteins using a novel sequence similarity-based method. Sci Rep, 12(1), 13739. doi: 10.1038/s41598-022-18021-1
Hits since March/2022 Last updated:

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HELP: Epitope Features

Here the user can select the parameters that the alignment must meet to consider a sequence fragment (target sequence) as a B-cell epitope.

Given the default parameters, here we present an example of an alignment that would result in the prediction of a linear B-cell epitope. Likewise, we show some alignments that would be descated and not considerated as positive hits:

HELP: Output options

If the option "Only neutralizing" is selected, BepiBlast, will only return B cell epitopes resulting from hits to neutralizing epitopes. If the option "Map in sequence" is selected, BepiBlast colors the sequence residues into an RGB scale, which enable mapping B cell epitopes in the query seqeunce.



Alvaro Ras Carmona, PhD Student

Dr. Pedro A Reche, Group Leader

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